Determination of selamectin in dog plasma by high performance liquid chromatography with automated solid phase extraction and fluorescence detection

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Determination of selamectin in dog plasma by high performance liquid chromatography with automated solid phase extraction and fluorescence detection.

A method is described for the determination of selamectin in dog plasma, using High-Performance Liquid Chromatography (HPLC) with fluorescence detection (excitation and emission wavelengths fixed at 355 and 465 nm, respectively). The fluorescent derivative was obtained by condensation reaction with trifluoroacetic anhydride and N-methylimidazole. The method employs 1 mL plasma samples and gives...

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ژورنال

عنوان ژورنال: Veterinary Research

سال: 2001

ISSN: 0928-4249,1297-9716

DOI: 10.1051/vetres:2001137